- Type
- Sweetener
- How serious
- Low severity
- Evidence
- Emerging evidence
Why it is flagged
The bladder-tumour finding that once put saccharin on a carcinogen list was later shown to be a rat-specific mechanism, and it was delisted in 2000. It appears here only for the unsettled metabolic literature shared by non-sugar sweeteners.
Health topics it bears on
Sources
- List of Permitted Sweeteners (Lists of Permitted Food Additives) Health Canada, 2025
- Re-evaluation of saccharin and its sodium, potassium and calcium salts (E 954) as food additives European Food Safety Authority, 2024
- Use of non-sugar sweeteners: WHO guideline World Health Organization, 2023
- Report on Carcinogens, Fifteenth Edition – Appendix B: Substances Delisted from the Report on Carcinogens (saccharin) U.S. National Toxicology Program, 2021
- IARC Monographs Volume 73: Some Chemicals that Cause Tumours of the Kidney or Urinary Bladder in Rodents and Some Other Substances (includes saccharin and its salts) International Agency for Research on Cancer, 1999
Also listed as
e954, saccharin, saccharine, sodium saccharine, saccharine de sodium, saccharine sodique, natriumsaccharin, saccharin natrium, sacarina, sacarina sodica, saccarina, saccarina sodica